[Hypoxic training in rehabilitation of patients at the early stages of recovery after SARS-CoV-2 pneumonia]. / Rol' gipoksicheskikh trenirovok v reabilitatsii patsientov na rannikh srokakh vosstanovleniya posle pnevmonii, vyzvannoi virusom SARS-CoV-2.

OBJECTIVE: To evaluate efficacy and safety of hypoxic-hyperoxic therapy in rehabilitation after SARS-CoV-2 pneumonia. MATERIAL AND METHODS: There were 44 patients aged 49-75 years in early recovery period after previous SARS-CoV-2 pneumonia (ICD-10 U07.1 and U07.2). Patients were divided into 2 groups depending on treatment strategy: group 1 (n=23) - rehabilitation treatment with therapeutic exercises, massage and physiotherapy; group 2 (n=21) - basic procedures with hypoxic-hyperoxic therapy. RESULTS: At initial evaluation, we found positive tendencies of rehabilitation in both groups. There were no side effects associated with hypoxic-hyperoxic therapy in the second group. Patients positively perceived this method of rehabilitation. There were significant between-group differences in exercise tolerance (p<0.05). These data indicate more favorable physical recovery in the second group and similar improvement of psycho-emotional status in both groups. CONCLUSION: Hypoxic-hyperoxic therapy is effective and safe approach in rehabilitation of patients with previous SARS-CoV-2 pneumonia. It is necessary to continue searching for effective methods of rehabilitation and develop accurate rehabilitation methods for various groups of patients.

[The role of systemic ozone therapy in the rehabilitation of patients after COVID-19]. / Rol' sistemnoi ozonoterapii v reabilitatsii patsientov, perenesshikh COVID-19.

OBJECTIVE: To evaluate the effectiveness and safety of ozone therapy in rehabilitation of patients with previous COVID-19. MATERIAL AND METHODS: A randomized controlled clinical trial included 51 patients aged 29 - 78 years with SARS-CoV-2 pneumonia (J12.8). Patients were divided into 3 comparable groups depending on the complex of rehabilitation. In the first (control) group (n=17), a 10-day course included daily breathing exercises and physiotherapy for the lungs (drug electrophoresis and low-frequency magnetotherapy). In the second (main) group (n=18), rehabilitation was combined with daily intravenous infusions of ozonized saline with ozone concentration of 2.0 mg/l within 5 days with subsequent standard rehabilitation. In the third group (n=16), patients received 5 ozone therapy procedures every other day. To determine the effectiveness and safety of systemic ozone therapy in rehabilitation of patients with previous COVID-19, we analyzed oxygen saturation, laboratory data (D-dimer and C-reactive protein), need for oxygen support before and after rehabilitation course. Complaints and quality of life throughout the rehabilitation program were assessed using the EQ-5D questionnaire. RESULTS: All patients had positive changes of all parameters. There were no adverse reactions throughout the rehabilitation program and 2 months later. We observed higher effectiveness of rehabilitation with systemic ozone therapy. Moreover, daily ozone therapy had a better effect on laboratory parameters compared to ozone therapy every other day. CONCLUSION: Ozone therapy is safe and effective in complex rehabilitation of patients with previous COVID-19. Further studies of large samples are needed to determine indications and appropriate criteria for this rehabilitation program.

[Influence of therapeutic exercises and hardware massage in electrostatic field on lung damage in patients with novel coronavirus pneumonia]. / Otsenka vliyaniya lechebnoi gimnastiki i apparatnogo massazha v elektrostaticheskom pole na stepen' porazheniya legkikh u patsientov s pnevmoniei pri novoi koronavirusnoi infektsii.

OBJECTIVE: To analyze the efficacy and safety of therapeutic exercises and chest hardware massage in electrostatic field in patients with COVID-associated viral pneumonia. MATERIAL AND METHODS: We retrospectively analyzed 1551 patients admitted to the Clinical Hospital No. 1 (MEDSI Group JSC) with COVID-associated pneumonia between April 01, 2020 and June 15, 2021 (ICD-10 U07.1 and U07.2). Considering inclusion and exclusion criteria, we enrolled 153 patients. All patients were divided into comparable groups and subgroups depending on the methods of rehabilitation treatment and CT stage of viral pneumonia. Lung damage was assessed semi-automatically using Philips Portal v11 COPD software. Rehabilitation measures included therapeutic exercises and chest hardware massage in electrostatic field. therapeutic exercises. RESULTS: Therapeutic exercises significantly reduced severity of lung damage in patients with viral pneumonia CT-2 and no oxygen support (from 28.05% [28; 29.5] at admission to 15.3% [14.2; 19.3] at discharge). It was not observed in patients without rehabilitation treatment and in patients undergoing therapeutic exercises and massage in electrostatic field. CONCLUSION: Therapeutic exercises in patients with COVID-19 and baseline lung damage > 25% and < 50% (CT-2 stage) significantly reduce severity of lung damage at discharge compared to the control group.

Tunable continuous-wave operation of a Cr3+,Li+:Mg2SiO4 laser.

Room-temperature tunable cw laser oscillation of Cr3+ ions in forsterite crystals (Mg2SiO4) codoped with chromium and lithium has been demonstrated, for the first time to the authors' knowledge, in pumping a crystal with a Ti:sapphire laser into the first excited level of Cr3+ ions (4A2-4T2 transition). The laser is smoothly tunable in the region of 1095-1170 nm. A slope efficiency as great as 4.4% has been achieved.

Depressed cladding, buried waveguide laser formed in a YAG:Nd3+ crystal by femtosecond laser writing.

Depressed cladding waveguides have been formed in laser crystals by a tightly focused beam of a femtosecond laser. A laser based on a depressed cladding waveguide in a neodymium-doped YAG crystal has been demonstrated for what is believed to be the first time.

Directly diode-pumped tunable continuous-wave room-temperature Cr4+:YAG laser.

We report what is to our knowledge the first directly diode-pumped tunable (over 120 nm) continuous-wave Cr(4+): YAG laser, operating near 1.5 microm . At room temperature the laser delivered as much as 200 mW of power at 4 W of absorbed pump power. We also report observation of slow laser output degradation and bleaching in highly concentrated crystals, which we suggest is due to a photorefractive phenomenon.

Self-starting Kerr-lens mode-locked femtosecond Cr(4+):YAG and picosecond Pr(3+):YLF solid-state lasers.

We have observed true self-starting Kerr-lens mode locking in two distinct solid-state laser systems operating at room temperature by optimizing the cavity geometry to maximize the amplitude modulation with respect to the intracavity power variation. Pulses of 15 ps have been obtained from a Pr(3+):YLF laser system operating at 607 nm, and 53-fs pulses have been obtained from Cr(4+):YAG at 1.54 microm.

Passive mode locking and dispersion measurement of a sub-100-fs Cr(4+):YAG laser.

We report the passive mode locking of a Cr(4+):YAG laser by use of a moving mirror and the generation of pulses as short as 70 fs by use of Kerr-lens mode locking. The intracavity dispersion has been measured, and the laser performance has been related to water absorption lines.

Continuous-wave mode-locked Cr(4+):YAG laser.

A cw room-temperature Cr(4+):YAG laser, tuning from 1.37 to 1.51 microm, is described. Mode locking of this novel laser is reported for what is to our knowledge the first time.

Dual Q switching and laser action at 1.06 and 1.44 microm in a Nd(3+):YAG-Cr(4+):YAG oscillator at 300 K.

We report what is to our knowledge the first dual operation comprising laser action and Q switching of Cr(4+):YAG pumped intracavity by a Nd:YAG laser. This technique produced dual 1.06- and 1.44-microm pulses with 35- and 200-ns pulse widths, respectively. The Nd:YAG rod was pumped by a 1-ms flash-lamp pulse, resulting in a train of 1.06- and 1.44-microm pulse pairs at approximately a 30-kHz rate.

[Anesthesiology in urgent operations in treating heart wounds]. / Anesteziologiia pri ékstrennykh operatsiiakh po povodu raneniia serdtsa.

Experience of treating 11 patients with knife wounds of the heart in a central district hospital is reviewed. Limited preoperative period, intensive therapy of hemorrhagic shock, readiness of a surgical and anesthesiological teams to perform a wide range of resuscitation procedures in the course of the operation, prophylaxis, timely and adequate therapy of complications arising in the postoperative period--all help to obtain good results.